Tetrahydrocannabinol (THC)

Overview:  This drug is derived from a particular type of hemp plant called Cannabis Sativa and is commonly called Marijuana (Also spelled Marihuana).  Marijuana and related products (e.g., hashish and charas) is the drug of choice for many individuals (especially youth who cannot purchase alcohol).  While the drug acts similarly as alcohol, its primary site of action is within the synapse complex rather than the entire neuron.  Considering the level of use, potential medicinal properties, etc. many states have decriminalized or repealed a variety of marijuana laws 

Goals:  This section is designed to provide a review of marijuana and related compounds.  It will also provide an examination of sites of action and behavioral effects derived from THC.

Objectives:  To understand the history, pharmacokinetics and pharmacodynamics of THC related compounds.

Outcomes:  

KSA’s

3.            Describe the behavioral, psychological, physical health and social effects of psychoactive drugs including alcohol and tobacco on the consumer and significant others.

4.              Recognize the potential for substance use disorders to mimic a variety of medical and psychological disorders and the potential for medical and psychological disorders to co-exist with addiction and substance abuse.

5.         Be familiar with medical and pharmaceutical resources in the treatment of addictive diseases and other substance-related disorders.

102.      Describe warning signs, symptoms, and the course of substance use disorders.

Readings:   Julien,  Edition 10, Chapter 18 (or Julien, Edition 11,

                    Chapter 17)

Tasks:

1.  Read Chapter 18 of Julien, Edition 10 (or Chapter 17, Edition 11).  Pay close attention to how THC works on particular binding sites within g-protein related receptors.

2.  Answer the following study questions  1, 2 3, 7, 8, 9. 

3.  Review the material again in Julien regarding medicinal use of marijuana.  Then go to the web and review this website. http://stills.nap.edu/readingroom/books/marimed/
Then write a brief paper describing the issue of medicinal marijuana use.  What is your opinion?  Make sure you support your arguments well.  Note: (There are no correct answers here, I will grade you on the logic you apply to the topic.) 

4.  Send your completed materials to your instructor

Discussion  for Topic 8.