Comparing Mary Shelley's Frankenstein and James Whales Bride of Frankenstein

We are interested here in how the same story changes each time it is retold and whether and how these changes are or are not significant.

We are interested in how the retelling of the story:
1) Re-shapes our understanding and beliefs concerning monstrosity: good and evil

2) Reflects the given culture's existing understanding and beliefs concerning monstrosity: good and evil (cultural lens).

Examples: Magnum, P.I. murdering the Russian agent (Did You See The Sun Rise? 9/30/82).
Gilligan's Island vs. Survivor.

More to the (Frankenstein) point :

Prometheus
Adam and Eve, Satan and God
Paradise Lost
Frankenstein, or The Modern Prometheus
The Bride of Frankenstein
Do Androids Dream of Electric Sheep
Bladerunner

Film arguably had a much greater impact on 20th century Western Culture than did literature, so our generations' Frankenstein myth -- and its moral, cautionary theme -- is largely based on the Whale's interpretation of Shelley's story, not on Shelley's story itself.

Or, actually, our understanding of this myth and its message is likely mostly based on retellings such as Bladerunner or Terminator or, most recently, Spiderman etc.

Similarly, Shelley's understanding of the similar stories as told by the Greeks or in the Bible would have been influenced by Percy Shelley's poem Prometheus Unbound or Milton's retelling of Genesis in Paradise Lost etc.

In short, each time the same story is told, I different story is created....

We can most easily see this by comparing Shelley and Whales Frankenstein stories.

Discuss and describe how his version has shaped our cultural consciousness concerning morality and science or morality and knowledge in ways that are significantly different than those proposed by Shelley in her novel. Similarly we should consider how Shelley's interpretation of both the Prometheus myth differs from the original Greek, and, therefore, how Whales differs from the Greek as well. Finally, we should consider how Shelley and Whales' interpretations use and abuse Biblical mythology.

What are the major, significant differences between the two in terms of:
Dramatic Elements: Plot, Character, Setting, Symbol

And how do these major differences communicate:
1) The same overall thematic or "moral" message concerning the nature of monstrosity?

2) A significantly different thematic or "moral" message concerning the nature of monstrosity?

Compare especially how both artists (Shelley and Whale) use Biblical symbolism and allegory and how their very different interpretations radically change the thematic message itself.

How do these themes affect our perception of:
Scientific Knowledge
Technology
History
Adolf Hitler and the Holocaust
Terrorism and Revolution
Religion
Love
Nature
Life Itself